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The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesisprimarily via inhibition of cyclooxygenase-2COX-2
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Celebrex can increase your risk of fatal heart attack or strokeespecially if you use it long term or take high dosesor if you have heart diseaseEven people without heart disease or risk factors could have a stroke or heart attack while taking this medicine.
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continue your usual care while you use celebrex.