Enzyme inducers phenobarbital, carbamazepine, phenytoin, and rifampin shorten the half- life of doxycycline from a normal time of 16-17 hours to 10 hours.

Information about Doxycycline.
For children who weigh less than or equal to 99 pounds45 kgThe recommended dosage is 4.4 mg/kg divided into two doses on the first day of treatmentThis is followed by 2.2 mg/kg given as a single daily dose or divided into two dosesFor more severe infectionDoses of up to 4.4 mg/kg may be usedFor children weighing more than 99 pounds45 kgUse adult dosage.
Doxycycline is a prescription antibiotic medication indicated for the treatment of the following infections and diseasesRocky Mountain spotted fevertyphus fever and the typhus groupQ feverrickettsialpoxand prozac before pregnancy. tick feversrespiratory tract infectionsurinary tract infectionslymphogranuloma venereumpsittacosisornithosistrachomainclusion conjunctivitisuncomplicated urethral/endocervical/rectal infections in adultsnongonococcal urethritisrelapsing feverchancroidplaguetularemiacholeracampylobacter fetusbrucellosisbartonellosisgranuloma inguinaleEscherichia colienterobacter aerogenesShigella speciesAcinetobacter speciesanthraxUncomplicated gonorrheaSyphilisYawsListeriosisVincent’s infectionActinomycosisand infections caused by Clostridium species.
Doxycycline is a prescription antibiotic medication indicated for the treatment of the following infections and diseasesRocky Mountain spotted fevertyphus fever and the typhus groupQ feverrickettsialpoxand tick feversrespiratory tract infectionsurinary tract infectionslymphogranuloma venereumpsittacosisornithosistrachomainclusion conjunctivitisuncomplicated urethral/endocervical/rectal infections in adultsnongonococcal urethritisrelapsing feverchancroidplaguetularemiacholeracampylobacter fetusbrucellosisbartonellosisgranuloma inguinaleEscherichia colienterobacter aerogenesShigella speciesAcinetobacter speciesanthraxUncomplicated gonorrheaSyphilisYawsListeriosisVincent’s infectionActinomycosisand infections caused by Clostridium species.
PenicillinDoxycycline may interfere with how penicillin kills bacteriaIsotretinoinTaking isotretinoin and doxycycline together can increase your risk of intracranial hypertension.
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