In certain embodiments, the serpina-1 polypeptide comprises the amino acid sequence set forth as m ox dbqntksplfmgkwnptqk seq id no 2 .
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AffiliationCentre for Cognitive Ageing and Cognitive EpidemiologyDepartment of PsychologyUniversity of EdinburghEdinburghUnited Kingdom.
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AffiliationDepartment of Clinical BiochemistryRigshospitaletCopenhagen University HospitalCopenhagenDenmark.
AffiliationMRC Human GeneticsInstitute of Genetics and Molecular MedicineUniversity of EdinburghEdinburghUnited Kingdom.
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methods of the invention may be used to allow comparison of levels of serpina-1 and or albumin polypeptides in two or more samples, taken at different times, which may be used to detect the status of preeclampsia in a subject and allows evaluation of a preeclampsia treatment as well as evaluation of a treatment to prevent the onset of preeclampsia in a subject.