According to lexapro s package insert, patients treated with lexapro in clinical trials did not differ from placebo sugar pill treated patients with regards to important changes in body weight.
Information about Lexapro.
Potentially life-threatening serotonin syndrome has been reported with SSRIs and SNRIs as monotherapybut particularly with concomitant use of other serotonergic drugs and drugs that impair the metabolism of serotoninSerotonin syndrome has been reported with racemic citalopram.
The risk of administering methylene blue by non-intravenous routessuch as oral tablets or by local injectionor in intravenous doses much lower than 1 mg/kg with Lexapro is unclearThe clinician shouldneverthelessbe aware of the possibility of emergent symptoms of serotonin syndrome with such usesee WARNINGS AND PRECAUTIONS
Adverse events were associated with discontinuation of 3.5of 286 patients receiving Lexapro and 1of 290 patients receiving placeboThe most common adverse eventincidence at least 1for Lexapro and greater than placeboassociated with discontinuation was insomnia1Lexapro0placebo
In some casesa patient already receiving Lexapro therapy may require urgent treatment with linezolid or intravenous methylene blueIf acceptable alternatives to linezolid or intravenous methylene blue treatment are not available and the potential benefits of linezolid or intravenous methylene blue treatment are judged to outweigh the risks of serotonin syndrome in a particular patientLexapro should be stopped promptlyand linezolid or intravenous methylene blue can be administeredThe patient should be monitored for symptoms of serotonin syndrome for 2 weeks or until 24 hours after the last dose of linezolid or intravenous methylene bluewhichever comes firstTherapy with Lexapro may be resumed 24 hours after the last dose of linezolid or intravenous methylene bluesee WARNINGS AND PRECAUTIONS
Report any new or worsening symptoms to your doctorsuch asmood or behavior changesanxietypanic attackstrouble sleepingor if you feel impulsiveirritableagitatedhostileaggressiverestlesshyperactivementally or physicallymore depressedor have thoughts about suicide or hurting yourself.
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in spite of this benefit, lexapro also carries some troubling risks for anyone using it.