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After a favorable initial response is notedthe proper maintenance dosage should be determined by decreasing the initial dosage in small decrements at appropriate time intervals until the lowest dosage that maintains an adequate clinical response is reached.
Patients should be warned not to discontinue the use of corticosteroids abruptly or without medical supervisionAs prolonged use may cause adrenal insufficiency and make patients dependent on corticosteroidsthey should advise any medical attendants viagra amazon uk. that they are taking corticosteroids and they should seek medical advice at once should they develop an acute illness including fever or other signs of infectionFollowing prolonged therapywithdrawal of corticosteroids may result in symptoms of the corticosteroid withdrawal syndrome includingmyalgiaarthralgiaand malaise.
Confirmed Cushing syndrome in which further workup is needed to identify whether hormone excess is the result of cushing syndrome or other causes Standard 2-day testAfter determination of baseline serum cortisol or 24-hr urinary free cortisol2 mg PO q6hr for 2 daysurine for free cortisol is collected during testand serum cortisol is checked 6 hours after final dose Overnight testAfter determination of baseline serum cortisol8 mgtypicallyPO between 11:00 pm and midnightcortisol level tested between 8:00 and 9:00 AM on following morning IV testAfter determination of baseline serum cortisol1 mg/hr by continuous IV infusion for 5-7 hours.
>6 weeks0.6 mg/kg/day IV divided q6hr for first 2-4 days of antibiotic therapystarting 10-20 minutes before or simultaneously with first antibiotic dose 6 weeks0.6 mg/kg/day IV divided q6hr for first 2-4 days of antibiotic therapystarting 10-20 minutes before or simultaneously with first antibiotic doseclasscalc_link
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