Even more surprising, the clinical outcomes among the patients in the trial were heading in the wrong direction, with slightly higher numbers of heart attacks, strokes and revascularizations angioplasties or bypass procedures among those taking vytorin, even though the increases were not statistically significant.
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also, vytorin has not been studied in patients younger than 10 years of age or in premenarchal girls.
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nissen, md, called the results a stunning reversal for zetia and vytorin.
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Blazing sales of the two resulting drugs, vytorin and zetia, helped each company to recover from setbacks in the early part of the decade.
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