Exceeding the recommended dosage level of one bolus 500 mg oxytetracycline hydrochloride per 100 lb body weight every 12 hours, or administration at the recommended level for more than four consecutive days, may result in antibiotic residues beyond the withdrawal time.
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Age at the time of administrationAnterior primary teeth are susceptible to discoloration by systemic tetracycline from 4 months in utero through 9 months postpartumAnterior permanent teeth are susceptible from 3 months postpartum through age 7 years91.
Besides the use in humansthe tetracyclines are used in animal therapy to treat infections and promote growthOxytetracycline and chlortetracycline are two of the ten antimicrobials authorized in the United States as growth promoters for cattleJeong et al.2010
Tetracycline and minocycline are excreted primarily in urineDoxycycline is excreted primarily in the intestinal tract.
Tetracyclines are broad spectrum antibiotics often used to treat skinchesturethraland pelvic infectionsDoxycycline is indicated in a wide range of infections including syphilisLyme diseaseQ feverRocky Mountain spotted feverand plagueIt is also widely used for malaria prophylaxis.
HASANTALLENMCOOPERMANB.SAnhydrotetracycline is a major product of tetracycline photolysisJOrgChem.v.50p.1755-17571985Links
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