Schering-plough s earnings and share price have deteriorated over the past year due to a plunge in sales of vytorin and zetia, its biggest products, even as several of its most promising drugs move into very costly late-stage trials.
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Because clinical studies are conducted under widely varying conditionsadverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice.
ZETIA is indicated as adjunctive therapy to diet for the reduction of elevated sitosterol and campesterol levels in patients with homozygous familial sitosterolemia.
TABLE 3Mean Percent Difference at Week 6 Between the Pooled ZETIA Coadministered with Simvastatin Group and the Pooled Simvastatin Monotherapy Group in Adolescent Patients with Heterozygous Familial Hypercholesterolemia.
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